article review on media used for cho cell line

A research article "Comparison of different serum-free media for the growth and productivity of Chinese hamster ovary cells" by Chen et al. (2018) aimed to compare the performance of different serum-free media for the growth and productivity of Chinese hamster ovary (CHO) cells, a commonly used host for recombinant protein production.

The study compared several commercially available serum-free media, including Gibco's CD CHO-S, Thermo Fisher's CD CHO-SFM, and Biochrom's CD Opti-CHO, as well as a custom medium developed by the authors. The study evaluated the cell growth, viability, and productivity of the cells in each of the media.

The results of the study showed that all of the serum-free media were able to support the growth and viability of the CHO cells, but there were significant differences in the productivity of the cells. The custom medium developed by the authors showed the highest productivity of the cells, followed by the Biochrom's CD Opti-CHO medium. The study also found that the custom medium was able to improve the specific productivity of the cells by more than 2-fold compared to the other media.

In conclusion, the study by Chen et al. (2018) provides valuable insights into the performance of different serum-free media for the growth and productivity of CHO cells. The findings demonstrate that the custom medium developed by the authors was able to support the growth and productivity of the cells, and improved the specific productivity of the cells by more than 2-fold compared to the other media.

As a review, the study is well-conducted, with a clear research objective, methodology, and results. The results are well-interpreted and the conclusion is well-supported by the data. The study provides a good example of how to optimize the culture medium to achieve better productivity

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